The long and short of it: No!
While IPv6 may seem superfluous to us as far as, “SBS can’t possibly be using IPv6 since we don’t have it “enabled” on our network”, it does in fact play an important role on SBS 2008.
If IPv6 does get disabled in the SBS 2008 NIC’s properties, there are a number of problems that may happen: SBS Blog: Issues After Disabling IPv6 on Your NIC on SBS 2008. Most of those problems centre around Exchange 2007 SP1.
Note that the SBS Blog does include a proper methodology for disabling IPv6 if there is an absolute need for it. But, only if there is an absolute need for it!
Please remember to test any changes that are significant in nature on a virtualized lab version of the production SBS box before going about with those changes. Also, make sure the backups are good too!
- SBS Diva: Outlook Anywhere and IPv6.
- Amy Babinchak: SBS 2008 DNS Resolution on IPv6.
- TechNet: SBS 2008: Managing IP Addresses.
Microsoft Small Business Specialists
*All Mac on SBS posts will not be written on a Mac until we replace our now missing iMac!